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It was observed that SP blocked the phosphorylation of all these proteins (Fig

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Further previous animal studies report that irisin is implicated in cerebrovascular protective effects of exercise by alleviating ischemic neuron injury (Li et al., 2017

The synergistic GH stimulation promotes preferential fat loss while preserving or even enhancing lean muscle mass, a critical distinction from simple caloric restriction which typically results in loss of both fat and muscle tissue

Rausch PG, Moore TG