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For chronic weight management, tirzepatide works by engaging multiple hormonal pathways, including the GIP and GLP-1 receptors, which are crucial for metabolic regulation, blood sugar control, appetite management, and energy expenditure

Its pro-angiogenic properties make it potentially beneficial for any tissue where inadequate blood supply limits healing

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Since the characterization of disease-associated glial phenotypes in 2017, building on earlier pioneering discoveries, we focus here on disease-associated microglia (DAM) and disease-associated astrocyte (DAA) to reassess their contributions to glio-inflammation