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Eine sorgfltige Beachtung der Dosierungsanweisungen und eine schrittweise Anpassung knnen helfen, das Risiko von Nebenwirkungen zu minimieren

The score was obtained as the number of positive cells per one power field (magnification 200)

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Moreover, strict adherence to KD regimens carries potential risks, including impaired growth, micronutrient deficiencies, and metabolic complications such as hypoglycemia and acidosis (Neal et al., 2008

It is metabolized by the cytochrome P450 family (more specifically CYP2D6) to active metabolites such as endoxifen (4-OH-N-desmethyl-tamoxifen)

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