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Administered once weekly via subcutaneous injection, starting at 2.5 mg and titrated every 4 weeks to a maintenance dose of 515 mg

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These modify risk and may help decide how strongly to consider GLP-1 therapy for brain protection

Strong inhibition of the polyol pathway diverts glucose flux to protein glycation leading to rapid establishment of secondary complications in diabetes mellitus

1 Research also shows fisetin has other benefits like helping control inflammation, promoting cellular homeostasis (keeping cells stable), and acting as a natural senolytic meaning it might help clear out old, aged cells from tissues

Addressing storage issues before adjusting dosing prevents the cascade of problems that come from compensating for degraded compound