PubMed Del Prato, S., Kahn, S.E., Pavo, I., Weerakkody, G.J., Yang, Z., Doupis, J., Aizenberg, D., Wynne, A.G., Riesmeyer, J.S., Heine, R.J., Wiese, R.J., & SURPASS-4 Investigators
Detka J, Kurek A, Kucharczyk M, Gombik K, Basta-Kaim A, Kubera M, et al
467 Under hyperglycemic conditions, GLP-1RAs regulate hypertension by inhibiting carotid body function
Insulin resistance plays an important role in the pathophysiology of comorbid T2DM and depression and can be a trigger for dysregulation of insulin- and GLP-1-mediated signaling (both central and peripheral), neuroendocrine disorders (hypothalamicpituitaryadrenal system dysfunction and monoaminergic neurotransmission disorders), chronic low-intensity inflammation, oxidative stress, and disorders of the microbiota-gut-brain system, reducing the level of neurotrophic factors in the brain and changing synaptic plasticity
This supports the value of GLP-1 receptor agonists in personalized healthcare strategies
So, how do I use this code