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In mature adipocytes, noradrenaline (NE) released by the sympathetic nervous system binds to 3-adrenergic receptors, activating the guanine nucleotide-binding protein (Gs), which in turn stimulates adenylate cyclase (AC)

Farrell CP, Morgan M, et al

315 Given the critical function of glutamine metabolism, GLS inhibitors have been explored as potential CSC-targeting agents

2017 Aug 26;9(9)

[DOI] [PMC free article] [PubMed] [Google Scholar] Ramakrishnan M, Papolu PK, Satish L, Vinod KK, Wei Q, Sharma A.Emamverdian A, Zou LH, Zhou M

Our results serve as a first for a class B1 GPCR, highlighting the importance of GPCR-lipid interactions on receptor function and dynamics for this receptor class