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These findings suggest that intranasal GHKCu has the potential to attenuate features of AD, including cognitive decline, amyloid plaque accumulation, and neuroinflammation, and provide the rationale for further studies in aging mice, for example using an AAV vector containing sequences of A42 and mutant tau [48]

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Its involvement in sleep-associated hormonal rhythms makes DSIP particularly relevant for studying the relationship between circadian biology and endocrine signaling

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