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To further determine the importance of the PI3K/AKT signaling in NAC-modulated function, TSPCs were treated with, or without, NAC in the presence or absence of an PI3K/AKT inhibitor (LY294002), and the relative levels of PI3K/AKT phosphorylation and integrin 51 expression were analyzed by Western blotting

The current method presents a modified protocol that addresses the limitations of existing methods for measuring GPx activity

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Inhibiting succinate release worsens cardiac reperfusion injury by enhancing mitochondrial reactive oxygen species generation

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