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Many have years of evidence behind them

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*In a 68- and 72-week clinical trial studying Wegovy (2.4 mg) in patients without diabetes and with BMI 30, or BMI 27 with a weight-related condition, the average weight loss was 15% and 20%, when paired with diet and exercise changes (compared to 2.4% and 3.1%, respectively, with diet and exercise alone)

Yet there arent any medications approved by the FDA to treat it

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Side effects : Nausea, gastrointestinal upset, injectionsite reactions, water retention, joint discomfort, or blood sugar changes can occur, depending on the peptide