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Indeed the activation of prodrugs in GST overexpressing cells may lead to high concentrations of an active drug, as compared to normal cells with moderate enzyme levels

Glutathione may theoretically interact with chemotherapy medications, as some cancer treatments work partly by inducing oxidative stress in cancer cells

Imaging and densitometry analysis was performed by measuring the optical densities of specific bands using a GS-800 Calibrated Image Densitometer (Bio-Rad Laboratories Srl, Milan, Italy) or UVITEC Mini HD9 acquisition system (Alliance UVItec Ltd., Cambridge, UK)

49 Iron chelators may alleviate the effects of iron stasis and neurotoxicity on neurons