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Stanley MW, Horwitz CA, Levinson RM, Sibley RK

Beyond its role in inflammation, TXNIP markedly contributes to apoptosis induction (179)

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Neuronal GLP1R Mediates Liraglutides Anorectic but Not Glucose-Lowering Effect

[Our] basic thinking on AOD9604 is that the drug failed because it was made orally available, which likely reduced bioavailability and also potentially resulted in protein denaturisation in the gastrointestinal tract, which would have reduced the drugs activity