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A decrease in creatinine levels can arise from four main causes: Low creatinine levels generally develop due to a decrease in muscle mass, which can be related to age or diseases affecting muscle quantity

[DOI] [PubMed] [Google Scholar] 201.Lehrke M., Reilly M.P., Millington S.C., Iqbal N., Rader D.J., Lazar M.A

During Phase 1, detoxification, toxins from car exhaust, smoke, alcohol, caffeine, dioxin, drugs, radiation, heavy metals, pesticides, and other carcinogens are partially processed by specialized proteins inside mitochondria cytochromes

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