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Additionally, the chapter elucidates the regulatory mechanisms governing homocysteine metabolism and its implications for a range of pathological conditions, including cardiovascular diseases and neurodegenerative disorders

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These results highlight the fact that, although NAD + restoration is a biologically valid approach, its clinical effectiveness is now only supported by surrogate biomarkers rather than cognitive recovery

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Each subject underwent 4 trials separated by a minimum of a 3-week washout period