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As we noted in the CY 2025 OPPS/ASC final rule with comment period (89 FR 94514 through 94521), we believe that a methodological change to increase the importance of the Safety of Care measure group is appropriate

the steepest single-compound point is ~1.4 at 55 kg versus the 85 kg reference

Comment: A few commenters expressed concern regarding potential conflicts between the requirements for the Information Transfer PRO-PM survey and the OAS CAHPS guidelines

Some protocols suggest increasing by 1.25 mg when side effects are a concern, and at 5 mg/mL, that 1.25 mg increase is a clean 25-unit adjustment

The 20mg/ml format ensures the daily GS-441524 dose can be drawn and administered accurately

A whole-person approach