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Here based on a matched comparative study, we showed that L-carnitine administration was unable to accelerate VPA clearance, speed blood lactate level normalization or limit organ dysfunction

Laboratory test values continue to worsen, with evidence of lactic acidosis, prolonged prothrombin time, markedly elevated liver transaminases, elevated bilirubin (primarily indirect), renal function abnormalities, and hyperammonemia

10.1007/s10162-013-0404-1 12 CoffinA