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Theres also the overall risks that come with using GLP-1s

Combining them increases cumulative risk, particularly for people with a history of pancreatic inflammation

In phase 2 clinical trials, 2% of patients reported pancreatitis with a 12 mg dose

Unfortunately, weight loss is not as simple as filling a prescription

The clearest contraindications in the FDA labeling are a personal or family history of medullary thyroid carcinoma (MTC), the genetic condition MEN 2, and a known serious allergic reaction to the specific drug

That means roughly half of patients who accept an initial denial would have been approved had they appealed