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JL: Writing review & editing

Priority research needs include large-scale randomized controlled trials to establish efficacy and safety, dose-ranging studies to optimize treatment protocols, long-term safety studies particularly regarding cancer risk, and comparative effectiveness research with established therapies

NADPH is used as an electron donor to reduce oxidized GSH and TRX, thus maintaining antioxidant capacity in cells

Oral absorption is variable and correct administration affects absorption

Liu W, Yang Y, Li P, Zhou Q, Xie L, Han Y

The clinics effective cost per acquired TRT patient via cross-sell approaches zero