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UK dietary reference values recommend approximately 0.75g of protein per kilogram of body weight daily, though during weight loss, higher intakes (1.0-1.2g/kg/day) may help preserve lean muscle mass

The most common side effects are gastrointestinalnausea, vomiting, and constipationwhich typically appear early and decrease over time

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This situation feels different from other drug classes because it is: diabetes and obesity are massive markets, and beyond the FDA approved indicated populations, theres a swath of people interested in getting their hands on GLP-1 agonists off-label to help them lose a few extra pounds

Higher doses may be used under professional guidance, especially during periods of high oxidative stress