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Dao K et al

This central action contributes to weight loss by reducing hunger and caloric intake

doi:10.1016/j.cmet.2022.07.013

Key Takeaways In the Phase 3 TRIUMPH-1 trial (2026), retatrutide 12 mg produced an average 28.3% body-weight reduction at 80 weeks, with 45.3% of participants losing 30% or more ( New England Journal of Medicine / Eli Lilly, 2026 )

Reconstituted vial: NEVER freeze Freezing a reconstituted peptide solution causes ice crystal formation that physically disrupts the peptide's molecular structure

If you remember within 3 days of your scheduled injection, take the dose immediately and resume your regular weekly schedule