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DPP-4 may additionally influence metabolic control via its proteolytic effect on other regulatory peptides, but it has also been reported to affect insulin sensitivity, potentially mediated through its non-enzymatic interactions with other membrane proteins

2010 December

+6.5pp absolute difference First open-label head-to-head between single and dual receptor agonists

Since it affects neural pathways, some women experience headaches or heightened sensitivity

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