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Miao F, Li Y, Tai Z, Zhang Y, Gao Y, Hu M

PMID: 29182711

Why it matters: In tissue and cellular research, impurities can act as confounding variables that alter inflammatory or repair responses

Fluoroquinolone exposure tends to suppress the TCA cycle and activate the glyoxylate shunt, conserving carbon and reducing ROS while channeling electrons into NADPH/GSH synthesis

Contrary to these results with NAC, a methionineenriched diet impaired endothelium-dependent vasodilation in WKY control rats, consistent with the increase in blood pressure seen in these animals, indicating impaired bioavailability of NO (35)

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