Asterisks (*) indicate significant difference (P0.05) from control values, # indicate significant difference (P0.05) from ASA treated group and indicate significant difference (P0.05) as compared to BSO+ASA treated group
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These results indicate modest efficacy, with realistic expectations being 0.25-0.5 kg (0.5-1 pound) per week under optimal conditions
In cardiac models, Bock-Marquette et al., Nature 2004 reported that T4 activates integrin-linked kinase and Akt signalling, promoting cardiomyocyte survival, migration and improved function after coronary ligation in mice
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