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[2] It is also important to meet with the prescribing doctor at regular intervals to review the medication's effectiveness, manage any adverse effects, and alter the dosage if needed

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Compounded medications are made by licensed compounding pharmacies under FDA oversight

However, not all patients respond effectively to GLP-1R monoagonists, and higher doses aimed at increasing efficacy result in adverse gastrointestinal effects

Both methods were time-consuming, expensive and imprecise (Randle

Retatrutide is being developed for both obesity and type 2 diabetes but is not yet licensed for either indication in the UK