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Study Design and Population The trial enrolled 445 participants across three groups in a 1:1:1 randomization: Retatrutide 9mg group: 148 participants Retatrutide 12mg group: 149 participants Placebo group: 148 participants Participants had an average baseline weight of 112.7 kg (248.5 lbs) and a mean BMI of 40.4 kg/m

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Experts emphasize that people should not start or stop medications solely for brain health without talking to a healthcare provider and that lifestyle factors (healthy diet, physical activity, and blood sugar control) remain critical in dementia prevention