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doi:10.2174/138161209787185751

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Cytosolic arylamine N-acetyltransferase (NAT) deficiency in the dog and other canids due to an absence of NAT genes

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Despite the overall beneficial effects of selenium in maintaining cartilage homeostasis, strategies to supplement selenium or selenoproteins should be considered with care to avoid adverse health effects such as selenosis

In individuals with nutritional deficiencies (e.g., strict vegetarians without supplements), injections may be given less frequently or replaced by oral supplements once levels stabilize