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People who have gastrointestinal disorders like celiac disease or Crohn's disease or who have undergone weight-loss surgery may secrete too little hydrochloric acid or intrinsic factor

Pregnant or nursing women, individuals with active cancer, or those with severe renal impairment should avoid these protocols

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People with acne-prone skin, enlarged pores, or history of blackheads and whiteheads are more likely to purge

For TB-500, the situation is similar or thinner, with much of the strongest science attached to the parent protein Thymosin Beta-4 rather than the marketed fragment

Millet I, Vignery A