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On a U-100 insulin syringe, 1 mL = 100 units, so 2 mL fills the syringe to 200 units

Notably, mutations in TP53 not only change its conformation but also cause p53 aggregation, and p53 aggregation in cells is more consequential than conformational changes

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Because the glucagon receptor is highly expressed in the liver, adding GCGR agonism gives the molecule a tissue-specific mechanism for reducing hepatic fat and, hypothetically, addressing the inflammation and fibrosis that define MASH