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Associations between hepatic functions and plasma Amyloid-Beta Levels-Implications for the capacity of liver in peripheral Amyloid-Beta clearance

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Chambers et al, 1999a

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KEAP1 acts as a sensor for redox reactions, and together with CULLIN3, forms an E3 ubiquitin ligase complex responsible for targeting NRF2 for ubiquitination and subsequent degradation