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In PTC, high level of phosphoglycerate dehydrogenase (PHGDH), which catalyzes the process producing the precursor of serine as well as the first key enzyme of one-carbon metabolism, facilitates TC progression [160, 161]

The most commonly used dermal fillers used for lip injections includes Restylane, Juvederm Ultra, Juvederm Ultra Plus and Juvederm Volbella

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