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Using Cos7 cells we examined wildtype and E354Q GIP receptor signaling, analyzing cAMP and IP 1 accumulation as well as AKT, ERK1/2 and CREB phosphorylation

This is theoretical and not proven in clinical trials, but the mechanistic pathways are well-documented

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However, doctors may recommend taking B12 supplements after the age of 50 years as your ability to absorb B12 decreases with age

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