Activation of GLP-1R leads to an increase in intracellular cAMP and/or calcium, triggering signaling pathways including protein kinase A (PKA), exchange proteins directly activated by cAMP (Epac-2), phospholipase C (PLC), and extracellular signal-regulated kinase 1 and 2 (ERK1/2), thereby mediating effects on glycemic regulation, immune process, and inflammation
Int J Mol Sci (2020) 21:3688
Clin Exp Hepatol
Image 1. Hair follicle before remodeling signaled by GHK-Cu(Copper Peptide)
Copper peptides can also help reduce the appearance of crow's feet, which are wrinkles that form around the eyes due to repeated facial expressions, such as smiling and squinting
Statements Author contributions KL: Writing original draft, Writing review & editing