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Published evidence is summarized lower on the page

The majority circulates in the blood but is not directly available to the body and is excreted again

An earlier 12-week trial in 300 obese adults produced a genuine positive signal the 1 mg daily dosing arm showed a statistically significant 2.8 kg mean weight loss versus 0.8 kg in the placebo group and that result is what justified moving into the larger Phase IIb trial

The solution can be administered intramuscularly or subcutaneously, depending on the severity of the patient's condition

Following withdrawal of first dose use injection within 14 days

see Cyanocobalamin injection for medical use details