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In some cases, the insulin dose should be split into 2 injections at 2 different sites, since discomfort at the injection site may decrease when doses less than 50 units are used (for insulins with 100 units/mL concentration)

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GLP-1 therapy has been studied extensively and is considered safe when prescribed by a healthcare provider

Fukunaka A, Fukada T, Bhin J, Suzuki L, Tsuzuki T, Takamine Y, et al

2.Valenzuela PL, Carrera-Bastos P, Castillo-Garca A, Lieberman DE, Santos-Lozano A, Lucia A (2023) Obesity and the risk of cardiometabolic diseases