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Synthetic melanocyte stimulating hormone analogues, including structurally modified peptides, were highlighted as relevant tools for investigating how MC1R mediated responses may extend beyond pigmentation endpoints

For example, a notable study found that after drinking caffeinated coffee, fat oxidation (fat burning) increased by 29 percent in women with a healthy BMI (body mass index) and by 10 percent in those with obesity

Side effects primarily gastrointestinal can be significant and require monitoring

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