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The article lists personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, severe pancreatitis, and advanced diabetic retinopathy as the critical contraindications to assess during the initial evaluation

Younossi ZM, Zelber-Sagi S, Henry L, Gerber LH

doi: 10.1007/s40265-015-0410-1

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Some patients may experience palpitations or awareness of their heartbeat, particularly during the initial weeks of therapy