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In parallel, Eli Lilly developed tirzepatide (Mounjaro)--a dual GLP-1 and GIP receptor agonist

Rodent studies have shown C-cell tumours with GLP-1 receptor agonists, but the relevance to humans is unknown

There are other mechanisms by which circulating incretin mimetics can influence deep brain function without crossing the blood-brain barrier

Woo JS, Kim W, Ha SJ, Kim JB, Kim SJ, Kim WS, Seon HJ, Kim KS: Cardioprotective effects of exenatide in patients with ST-segment-elevation myocardial infarction undergoing primary percutaneous coronary intervention: results of exenatide myocardial protection in revascularization study

Heres a quick look at some key details about each medication

These medications work by increasing feelings of fullness by slowing the rate at which the stomach empties, which can help reduce the urge to overeat