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Caffeine inhibits activation of the NLRP3 inflammasome via autophagy to attenuate microglia-mediated neuroinflammation in experimental autoimmune encephalomyelitis

It also likely has many other effects on different parts of the body, notes Dr

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Our findings demonstrate that SEMA may substantially reduce DNP-induced activation of microglia and astrocytes in the spinal cord dorsal horn, indicating its potential clinical utility in DNP prophylaxis

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As a sealed powder, a lyophilized peptide can survive limited time at room temperature, which is why it can be shipped without a cold chain