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The long-acting GLP-1RAs have been altered in different ways to prolong plasma drug half-life

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Instituto de Salud Carlos III, Spain (grant CB16/11/00278 to F.M., co-funded with European FEDER contribution)

These medications, known as GLP-1 receptor agonists (GLP-1-RAs), offer promising therapeutic options for type 2 diabetes and obesity-related conditions, including cardiovascular disease (CVD) and non-alcoholic fatty liver disease (NAFLD) (6)