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Aminooxyacetic acid inhibits the malate-aspartate shuttle in isolated nerve terminals and prevents the mitochondria from utilizing glycolytic substrates

Consecutive illumination of discs from mature Arabidopsis leaves, for periods of 5, 15, 30 and 60 min, each of which was followed by fluorimetric time-lapse measurements, revealed a pronounced reduction of the cytosolic NAD pool as monitored by Peredox ( Figure 4D ) [23]