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Estrogen is responsible for increased collagen production, hydration, and barrier function

Evaluation of oxidative stress level: Total antioxidant capacity, total oxidant status and glutathione activity in patients with COVID-19

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10.1038/s41598-019-55473-4 62 GiloteauxL.LiJ.HornigM.LipkinW

By 4 weeks, positive effects were observed in the collagen peptides group compared with the placebo group for skin elasticity, wrinkle visibility, and nail color, which continued when the analysis was performed at 12 weeks

By encouraging extracellular matrix remodeling , copper peptides improve skin texture, reduce fine lines , and restore firmness