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Under normoxic conditions, p53 directly limits glucose uptake by repressing the transcription of GLUT1 and GLUT4, and induces TIGAR expression, thereby reducing PFK1 activity

The high proline content (4 of 15 residues, including a triple Pro-Pro-Pro stretch at positions 3 to 5) gives BPC-157 unusually good resistance to gastric and intestinal proteases, which is why some published animal work uses oral administration

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Tears in the inner two-thirds are far less likely to heal without intervention due to limited blood flow

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