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Delta sleep-inducing peptide (DSIP)-like immunoreactivity in gut: coexistence with known peptide hormones

doi: 10.1007/s13197-020-04360-2 132 AliAOonCCChuaBLFigielAChongCHWojdyloAet al

This mutation results in protein accumulation within the endoplasmic reticulum (ER) of hepatocytes and other AAT-producing cells, which leads to ER stress or an aberrant inflammatory response

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It seems to downregulate pro-inflammatory cytokines while promoting an environment conducive to healing