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Though the FDA and Novo Nordisk have made these specifications, it is legal and in fact commonplace for a doctor or nurse practitioner to prescribe them to people who dont fit the criteria, known as off-label use

Desikan, R

Tirzepatide targets the GLP-1 receptor and another hormone called GIP

Valdes-Sustaita et al., 2021)

Some patients report fatigue during tirzepatide treatment, particularly during the early treatment phase or with dose escalation, though this is not among the most common adverse events in clinical trials

For example, a shoulder that feels stuck or keeps losing range of motion can be a sign of frozen shoulder in menopause