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Yu and Gao 2015

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DOI: 10.1056/NEJMoa1004409

While short-term preclinical studies suggest favorable safety, chronic administration effects on angiogenesis, growth factor signaling, and tissue remodeling over years of use remain unknown

Results and discussion Effect of L

This interaction has been proposed as a mechanism by which the peptide may counter oxidative stress, which is often mediated by reactive oxygen, nitrogen, or carbonyl species