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The proposed signaling pathway regulating vascular mimicry is via PI3K/AKT (109)

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Additionally, sleep disturbances were found to increase the risk of AA in patients with other autoimmune conditions such as Hashimotos thyroiditis and rheumatoid arthritis (Seo et al., 2018)

Abbreviations ASCA anti- Saccharomyces cerevisiae antibody FGID functional gastrointestinal disorders GF germ-free IEB intestinal epithelial barrier IBD inflammatory bowel disease IBS irritable bowel syndrome IBS-C constipation-predominant irritable bowel syndrome IBS-D diarrhea-predominant irritable bowel syndrome IBS-M irritable bowel syndrome with mixed bowel habit LPS lipopolysaccharides SCFA short-chain fatty acids

Nature 616 , 159167 (2023)

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