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Further protein-protein interaction and pathway enrichment analysis were done by exporting the final matrix to STRING database

Quantitative PCR was then performed on a real-time PCR system using SYBR Green-based reagents

Activated type I NKT cells release perforin/granzyme to induce tumor cell apoptosis, express FasL to initiate apoptosis via binding to tumor cell Fas, and secrete cytokines (IFN-, IL-4, tumor necrotic factor-) to enhance NK/CD8 + T cell cytotoxicity (106)

In addition, it is widely accepted that obesity is a major risk factor for the disease, which can also alter an individuals treatment response to certain disease-modifying therapies

E., Nagy, P