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L., Ledoux, X., Mozziconacci, M
Coates et al
318,319,320 Furthermore, stability can be improved without compromising drug activity by optimizing the number and modification positions of 2-F and 2-OME groups on both strands of double-stranded siRNA, leading to substantial efficacy improvements
Their results suggest that early inhibition of M1 (pro-inflammatory) activation and support of M2 (anti-inflammatory) activation can shift the neuroinflammatory milieu towards tissue repair and recovery
Pharmacology 1996
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