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The interplay between hyperglycemia and oxidative stress contributes to the pathogenesis of diabetic complications, including neuropathy, nephropathy, retinopathy, and cardiovascular diseases [172]

That said, GLP-1s are not right for everyone

Moreover, the body depends on this chemical to mend cells

Instruct patients to contact their health care provider as soon as possible if they experience symptoms of heart failure, including increasing shortness of breath, rapid increase in weight or swelling of the feet [see Warnings and Precautions (5.2)]

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It takes several years to build the kind of capacity youre dealing with here, so its a daunting task to get it all in place. That head start is compounded by the fact that these drugs are potentially useful for a broad number of conditions, not just obesity and diabetes