10.1242/jcs.073874 83 KimJ.-Y.JoJ.LeemJ.ParkK.-K
Mitochondrial protein associated with both outer and inner membranes (Khaminets et al., 2016)
The solute carrier 44A1 is a mitochondrial protein and mediates choline transport
patients with severe gastrointestinal disease or gastroparesis may not be suitable candidates Hypersensitivity reactions : Including anaphylaxis, have been reported rarely Injection site reactions , including erythema, pruritus, or induration, occur in approximately 25% of patients and are generally self-limited
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As do other arsenicals, it induces G 2 /M cell cycle arrest and triggers apoptosis through disruption of mitochondrial functions and JNK activation and is responsible for reactive oxygen species production (Diaz et al., 2008)