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Second, although the conjugation of the toxic intermediate NAPQI by glutathione is an important protective mechanism, it occurs after the production of NAPQI, while glucoronidation removes APAP before the production of NAPQI

PLoS Biol 2018;16:e2006203

Mechanism of the regulation of organic cation/carnitine transporter 1(SLC22A4) by rheumatoid arthritis-associated transcriptional factor RUNX1 and inflammatory cytokines

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